CHEMICAL NAME: 17a-methyl-17b-hydroxy-1,4-androstadiene-3-one
HALF-LIFE: 4.5 – 6 hours
ANABOLIC RATING: 90 – 210
ANDROGENS RATING: 40 – 60
Methandrostenolon (or also methandienone) is substantially 17-alkylated derivative of testosterone with a double bond between the first and second carbon. It binds weakly to androgen receptors and therefore falls within the so-called steroids of II. Type. However, it compensates for the longer half-life and weak affinity for SHBG (binding globulin to sex hormones).It is by far the most popular steroid, and many athletes consider him the best steroid ever produced. Not for nothing it was known as the “Breakfast of Champions”. Due to the high water retention it is obviously not a steroid suitable for a definitionperiod. However, it is an excellent substance for obtaining good strength and muscle mass in bulking phase.
Although methandrostenolon differs from boldenone only by alkylation on the 17th carbon, its side effects are much stronger, especially at doses of 20-30 mg daily. Although its susceptibility to aromatize is weaker than that of testosterone, the resulting estrogen 17a-methylestradiol is much more potent than estradiol. Water retention and high blood pressure are therefore quite common, and already at low doses. Taking Clomid or Nolvadex during the cycle minimizes these effects. Methandrostenolon is also 17-alpha alkylated compound, which is quite toxic to the liver. Increase in liver function values occurs at doses above 10 mg per day. Although the use of methandrostenolone is generally associated with positive feelings of good cheer, at high dose (over 50 mg) it may result in an increase in aggression.
This material is used to limit protein catabolism after burns, after difficult operations, in infectious and febrile diseases. It is also combined with other drugs in the treatment of osteoporosis. For women in treatment of breast cancer and in Addison’s disease. In children, the use of growth delays in puberty and also combined with other drugs in the treatment of various chronic diseases.
Although Methandrostenolon through the action of 5-alpha reductase changes into a highly potent 5-alpha dihydromethandrostenolon, the reaction takes place in the human body only to a negligible extent. Methandrostenolon is itself quite a bit androgenic, so in some cases there is extremely strong acne and hair loss appears.
Taking Dianabol aready after a very short time undermines own production of androgenic hormones, so after discontinuation normally 80-90% gains in volume and strength disappear. Even a dose of 15 mg daily for 8 weeks lead in athletes to drop of body testosterone at a dramatic 69%. Other studies show a 30-40% reduction in the body’s own testosterone after 10 days of treatment with doses of 20 mg. After the treatment, it is therefore required to use the PCT.
In view of the relatively short half-life of action in the body (about 4.5 hours), which is more reduced at the date of exercise, the recommended intake is 2-3 times a day. The therapeutic dose is in the range of 2 – 8 mg daily for 6 weeks. Effective dosage for athletes’ ranges usually between 15-30 mg daily. Intermediate and advanced users use 30-50 mg day. Professional bodybuilders also use twice the amount 80-100mg per day. Such a high dosage is often very unnecessary and, moreover, carries an increased risk of adverse effects on the health of the body. When using methandienone, one needs to think about the use of herbal liver protection substances for its regeneration. Methandienone is undetectable in urine after about 2 months.
|Rapid increase in muscle mass and strength||easily aromatizes to estrogen|
|Enhances protein synthesis||is highly toxic to the liver|
|Increases appetite||risk of gynecomastia|
|Enhances immunity and IGF-1||increases blood pressure due to excessive water retention|
|In therapeutic doses increases collagen synthesis||suppresses natural production of androgenic hormones|
|Causes an increase in the number of red blood cells (fast blood supply to the muscles )||causes hair loss and hair growth|
|Low price||risk of acne|